01.

What is Labskin-S?

Labskin is a full thickness human skin model designed for testing cosmetics, skincare products, and pharmaceuticals. It replicates the structure and properties of human skin, offering a more ethical and practical alternative to animal testing. The skin model can be used in a variety of experiments, including those related to hydration, irritation, absorption, and efficacy.

02.

What is Labskin made of?

Labskin is typically made from a combination of human-derived cells, such as keratinocytes and fibroblasts, cultured in a specialized medium. The skin model is designed to closely mimic the stratified structure of human skin, with a viable epidermis and dermis. It is also engineered to be biocompatible and capable of being used for a range of in vitro tests.

03.

How is Labskin used in cosmetic testing?

Labskin is used for a variety of testing purposes, including:

Anti-aging and anti-wrinkle tests to assess the impact of products on skin regeneration and elasticity.

Skin irritation tests to assess the potential for a product to cause irritation.

Moisturization and hydration tests to measure the effects of products on skin moisture levels.

Absorption studies to determine how well ingredients penetrate the skin.

Sun protection factor (SPF) testing to evaluate the effectiveness of sunscreen products.

04.

Is Labskin a replacement for animal testing?

Yes, Labskin is often used as an ethical alternative to animal testing. It provides researchers with a tool to conduct experiments on a skin model that closely mimics human skin without the ethical concerns or regulatory issues associated with using animals.

05.

How accurate is Labskin compared to human skin?

Labskin is designed to replicate the characteristics of human skin as closely as possible, including factors such as skin barrier function, absorption, and hydration. However, while it provides a highly realistic model for many types of testing, it is still not identical to human skin in all aspects.

06.

Can Labskin be used for testing skin microbiome products?

Yes, Labskin can be used to test products that interact with the skin’s microbiome. Because Labskin models can support the growth of various skin bacteria, they are useful for studying how products affect microbial communities on the skin.

07.

How do you maintain Labskin during testing?

Labskin must be kept under specific conditions to maintain its viability. This includes maintaining appropriate temperature, humidity, and nutrition levels during testing. The model is typically incubated in a humidified environment at 37°C to replicate the natural conditions of human skin. Additionally, it may require a regular supply of fresh medium and careful monitoring for signs of degradation.

08.

What are the advantages of using Labskin for testing over other skin models?

Ethical Benefits: It provides an ethical alternative to animal testing.

Reproducibility: Labskin allows for more consistent and reproducible results compared to human or animal testing.

Skin Microbiome – Labskin can support full skin microbiome on it’s surface, including bacteria, yeast, fungi and viruses.

Human-like Properties: It closely mimics human skin, allowing for more accurate results when testing skin care, pharmaceutical products, or cosmetics.

Cost-effective: It can be more cost-effective than clinical trials or animal testing, especially for preliminary testing.

Reduced Regulatory Barriers: Using a synthetic skin model can help companies comply with international regulations that are increasingly restricting animal testing.

09.

Is there a shelf life for Labskin?

Yes, Labskin has a limited shelf life depending on the storage conditions. If stored at the proper temperature and in appropriate conditions, it typically lasts for 10-14 days. This allows for repeat applications and testing of products.

10.

How do you find out more?

Have more questions about Labskin-S that requires our experts to answer then drop the team your question at info@labskin.co.uk